News

Optica Fellows logo
November 2025: Matt has been elected a Fellow Member of Optica by the Society’s Board of Directors. He is being recognized “For pioneering contributions to super-resolution microscopy, single-molecule imaging, and the development of innovative nanoscale sensing techniques.” Matt is deeply honored by the recognition, and extends his special thanks to all Lew Lab members, collaborators, and mentors, past and present!
Oumeng and Yuanxin align a laser in lab
June 2023: Our lab has received a five-year $2 million Maximizing Investigators’ Research Award (MIRA) from the National Institutes of Health (NIH) to develop adaptive six-dimensional microscopy. [WashU Source]
Outstanding Faculty Award recipient Dr. Matthew D. Lew. Photo credit: Ron Klein.
April 2023: I have received a 2023 Outstanding Faculty Award from the Graduate Student Senate. The awardees were recognized at a ceremony organized by the GSS. Thank you, students, for this honor!
Brookings Hall and shield
April 2022: The Washington University in St. Louis Board of Trustees has promoted me to the rank of Associate Professor with tenure. Onward and upward! [WashU Source]

My lab develops cutting-edge imaging technologies for visualizing the intricate dynamic behaviors of biomolecules in living organisms.

I work across the fields of super-resolution fluorescence microscopy, single-molecule spectroscopy, molecular imaging, and biophotonics. My research focuses on combining novel molecular and nanoparticle tags with modern optical designs and sophisticated image processing algorithms to create new imaging technologies for bioscience and medical applications.

Visit my lab's website.